What is SPRAVATO®?
What it is:
SPRAVATO® is a nasal spray version of esketamine, a form of ketamine approved by the FDA for treatment-resistant depression and depressive symptoms in adults with suicidal thoughts.
What is TMS?
Transcranial Magnetic Stimulation (TMS)
How it works:
A device placed on the left side of your scalp sends painless magnetic pulses to stimulate neurons in an area of the brain called the prefrontal cortex. This helps "reset" brain activity in people with depression by improving communication in mood-regulating circuits.
What to expect:
- Outpatient sessions 5 times/week for a total of 35 sessions
- The first appointment is the ‘mapping’—where’ we use our technology to determine something called your motor threshold. This allows us to find your treatment threshold, which is 120% of the motor threshold, and the level of stimulation we give you at each treatment
- Sessions last about 20–40 minutes each
- No sedation - you can drive yourself to and from appointments!
Side effects:
- Mild headache or scalp discomfort
- Very low risk of serious side effects - no memory loss as compared to electroconvulsive therapy (ECT)
Not recommended in patients with:
- Intracranial metal implants such as cochlear implants, aneurysm clips, or stents
- Presence of other implantable medical devices, such as pacemakers
- History of adverse events related to previous TMS therapy
Caution in those with pregnancy, severe or recent heart disease, intracranial stimulation electrodes, cardiac stents or pacemakers, hearing impairment, epilepsy, or elevated intracranial pressure.
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