What is TMS?
TMS is a non-invasive brain stimulation therapy that uses gentle magnetic stimulation on specific areas of the brain involved in mood regulation.
What it is IV Ketamine?
IV Ketamine Infusion Therapy
How it works:
It modulates glutamate activity in the brain, leading to rapid antidepressant effects - often within hours!
What to expect:
- Urine drug screening required prior to treatment
- 1.5-2 hour long appointment, where ketamine is infused via IV catheter in office
- Typically 2 treatments/week over a period of 3 weeks for 6 total treatments
- 60 mL infused over a period of 40 minutes, with an additional 30 minute recovery period following treatment
- Vitals are monitored every 5 minutes during the treatment period. Patient is connected to a blood pressure monitor, oxygen monitor and EKG
- Blood pressure checked every 15 minutes in recovery period
- Due to sedative effects, designated driver is required to and from each appointment
- Option of ongoing maintenance as recommended by provider
Side effects:
- Dizziness, nausea, sedation, dissociation (feeling detached from reality)
- Short-term increase in blood pressure
Not recommended in patients with:
- psychosis, even if it is a symptom of a major depressive episode
- neurocognitive disorders, including dementias
- traumatic brain injury that is symptomatic
- alcohol use disorder or other substance use disorder
- use of illicit substances - must be clean of all illicit substances throughout treatment period
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