Depression is Real. You’re Not Alone.
Across the United States and around the world, rates of depression are rising — especially among youth and adults — and it’s something many of us or our loved ones will face at some point in life.
What it is IV Ketamine?
IV Ketamine Infusion Therapy
How it works:
It modulates glutamate activity in the brain, leading to rapid antidepressant effects - often within hours!
What to expect:
- Urine drug screening required prior to treatment
- 1.5-2 hour long appointment, where ketamine is infused via IV catheter in office
- Typically 2 treatments/week over a period of 3 weeks for 6 total treatments
- 60 mL infused over a period of 40 minutes, with an additional 30 minute recovery period following treatment
- Vitals are monitored every 5 minutes during the treatment period. Patient is connected to a blood pressure monitor, oxygen monitor and EKG
- Blood pressure checked every 15 minutes in recovery period
- Due to sedative effects, designated driver is required to and from each appointment
- Option of ongoing maintenance as recommended by provider
Side effects:
- Dizziness, nausea, sedation, dissociation (feeling detached from reality)
- Short-term increase in blood pressure
Not recommended in patients with:
- psychosis, even if it is a symptom of a major depressive episode
- neurocognitive disorders, including dementias
- traumatic brain injury that is symptomatic
- alcohol use disorder or other substance use disorder
- use of illicit substances - must be clean of all illicit substances throughout treatment period
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What is TMS?
TMS is a non-invasive brain stimulation therapy that uses gentle magnetic stimulation on specific areas of the brain involved in mood regulation.
What is SPRAVATO®?
What it is:
SPRAVATO® is a nasal spray version of esketamine, a form of ketamine approved by the FDA for treatment-resistant depression and depressive symptoms in adults with suicidal thoughts.
Understanding Alternatives for Treatment-Resistant Depression
Medications are not your only option!
If you or a loved one are living with treatment-resistant depression, you’re not alone—and you do have options. Here are three advanced treatments that may offer relief when traditional antidepressants haven’t worked.
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